Hey there, welcome!

I’m Lars Dornfeld, a computational protein designer fascinated by structural bioinformatics, de novo protein design, and machine learning in biology.

I began my scientific journey in the wet lab, engineering proteins and working in chemical biology. Later, I shifted to developing computational methods.


At the moment, I am mainly working on the adaptation of fixed-backbone sequence design models and structure–sequence cogeneration models for conditional generation tasks. I am also interested in fragment-based design, which allows shortening the wet-lab–computation cycles.

I’m a PhD student in the Biomolecular Design Group at the Max Planck Institute of Biochemistry (Munich), advised by Prof. Lukas Milles, with Prof. Karsten Borgwardt guiding my deep learning work.

If not in the lab, you will most probably find me in the mountains hiking, mountain biking, or camping…